08:45 – 09:00
Welcome words
Michael Heneka, Director, Luxembourg Centre for Systems Biomedicine
Session 1: Microglia
09:00 – 10:00
Plenary Talk 1: The role of neuron-glia-immune signaling
Beth Stevens, Harvard Medical School, USA
10:00 – 10:30
Trem2 and other genetic risk factors in AD
Gary Landreths, Indiana University, USA
10:30 – 11:00
Coffee break (posters & industry exhibition)
11:00 – 11:30
TREM2 and network dysfunction
Lennart Mucke, Gladstone Institute
11:30 – 12:00
The role of microglia-neuron crosstalk in health and disease
Tarja Malm, University of Eastern Finland
12:00 – 12:15
Luxembourg National Research Fund presentation
12:15 – 13:30
Lunch (posters & industry exhibition)
13:30 – 14.00
Poster session
Session 2: Oligodendrocytes
14:00 – 15:00
Plenary Talk 2: The role glia cells in de- and remyelination
Mikael Simons, TU Munich
15:00 – 15:30
The function of oligodendrocytes in AD
Klaus Armin Nave, U. Göttingen
15:30 – 15:45
Blitz Talks (selected from abstracts)
15:45 – 16:15
Coffee break (posters & industry exhibition)
Session 3: Astrocytes
16:15 – 16:45
Reactive astrocytes in neurodegeneration
Shane Liddelow, New York University
16:45 – 17:15
The epigenetic and metabolic control of astrocytes
Francisco Quintana, Harvard Medical School
Session 4: Epigenetics
17:15 – 18:15
Epigenetic mechanisms underlying Alzheimer’s disease
André Fischer, University of Göttingen
18:15 – 18:45
Transition between epigenetic states within the oligodendrocyte lineage
Gonçalo Castelo-Branco, Karolinska Institute
Session 5: Inflammasomes & cGAS/STING
9:00 – 10:00
Plenary Talk 3: Inflammasome inhibitors as new anti-inflammatory therapies
Kate Schroeder, University of Queensland
10:00 – 10:30
The role of cGAS/STING-IFN in tauopathies
Li Gan, Cornell University
10:30 – 11:00
Coffee break (posters & industry exhibition)
11:00 – 11:15
Blitz talks (selected from abstracts)
11:15 – 11:45
TBC
Session 6: Neurodegeneration
11:45 – 12:45
Plenary Talk 4: The interplay between tau pathology and neuroinflammation
Maria Grazia Spillantini, Cambridge University
12:45 – 13:45
Lunch (posters & industry exhibition)
13:45 – 14:15
Poster session & industry exhibition
14:15 – 14:45
The inflammatory regulation of APP processing and Aβ pathology
Magdalena Sastre, Imperial College London
14:45 – 15:15
The role of CD300f positive microglia in Alzheimer’s disease
Hugo Peluffo, University of Barcelona
15:15 – 15:30
Blitz talks (selected from abstracts)
15:30 – 16:00
Effects of glial senescence on neurodegeneration
Darren Baker, Mayo Clinic
16:00 – 16:30
Coffee break (posters & industry exhibition)
Session 7: Technical Developments
16:30 – 17:30
Plenary Talk 5: The use of snRNA-seq technologies in studying age-related pathologies
Naomi Habib, Hebrew University
17:30 – 17:45
Blitz talks (selected from abstracts)
17:45 – 18:15
The metabolome of the aging brain
Oliver Fiehn, University of California, Davis
18:15 – 18:45
The de novo proteome in AD mouse models
Eric Klann, New York University
18:45 – 21:30
Networking dinner with poster session and industry exhibition
Session 8: Clinical Aspects of Neuroinflammation
9:00 – 10:00
Plenary talk 6
10:00 – 10:30
Imaging of neuroinflammation
Paul Edison, Imperial College London
10:30 – 11:00
Coffee break (posters & industry exhibition)
11:00 – 11:30
Inflammatory biomarkers in CSF and blood
Charlotte Teunissen, Amsterdam University
11:30 – 12:00
Cell subtype-specific effects of genetic variation in Alzheimer’s disease
Philip de Jager, Columbia University
12:00 – 12:15
Blitz talks (selected from abstracts)
12:15 – 13:00
Lunch (posters & industry exhibition)
13:00 – 13:30
Poster session & industry exhibition
Section 9: Neurodegeneration Pathology
13:30 – 14:30
Plenary Talk 7: The structures of pathological amyloid filaments
Michel Goedert, Cambridge University
14:30 – 15:00
The impact of TD-43 proteinopathy
Dietmar Thal, University Leuven
15:00 – 15:15
Blitz talks (selected from abstracts)
15:15 – 15.45
Coffee break (posters & industry exhibition)
15:45 – 16:15
Amyloid-like fibrillar protein aggregates in NDs
Seung-Jae Lee, Seoul National University
Session 10: Neurotransmitters
16:15 – 17:15
Plenary Talk 3: The cholinergic system in health and disease
Hermona Soreq, Hebrew University
17:15 – 17:45
The role of type I interferon response in AD
Wei Cao, UT Health Houston