Charlotte Teunissen

Charlotte Teunissen is Professor in Neurochemistry and Chair of the Neurochemistry lab at  Amsterdam UMC’. Her drive is to improve care of patients with neurological diseases by developing body fluid biomarkers for diagnosis, stratification, prognosis and monitoring treatment responses. Studies of her research group span the entire spectrum of biomarker development, starting with biomarker identification, by –omics methods, followed by assay development and analytical validation, and extensive clinical validation and implementation in clinical practice.

She has extensive expertise with assay development using state of the art technologies, such as mass spectrometry and antibody-based ultrasensitive immunoassays, and in vitro diagnostic technologies for clinical routine lab analysis. She is responsible for the well-characterised biobank of the Amsterdam Dementia cohort, containing >10,000 paired CSF and plasma samples of individuals visiting the memory clinical of the Alzheimer Center Amsterdam  (a.o. controls, patients with Alzheimer, Frontotemporal, Lewy Body dementia).She (co-)leads several collaborative international biomarker networks, such as the Society for Neurochemistry and routine CSF analysis, the Alzheimer Association-Global Biomarker Standardization Consortium, and Coral proteomics consortium. She coordinates the Marie Curie MIRIADE project, aiming to train 15 novel researchers into innovative strategies to develop dementia biomarkers (10 academic + 10 non-academic centers), and the JPND bPRIDE project, that aims to develop blood based biomarkers for early differential dementia diagnoses.