08:45 – 09:00
Welcome words
Michael Heneka, Director, Luxembourg Centre for Systems Biomedicine
Session 1: Microglia
09:00 – 10:00
Plenary Talk 1: The role of neuron-glia-immune signaling
Beth Stevens, Harvard Medical School, USA
10:00 – 10:30
Microglia regulation of activity-dependent changes in neuronal metabolism and translation
Eric Klann, New York University
10:30 – 11:00
Coffee break (posters & industry exhibition)
11:00 – 11:30
TREM2 and network dysfunction
Lennart Mucke, Gladstone Institute
11:30 – 12:00
The role of microglia-neuron crosstalk in health and disease
Tarja Malm, University of Eastern Finland
12:00 – 12:15
Luxembourg National Research Fund presentation
12:15 – 13:30
Lunch (posters & industry exhibition)
13:30 – 14.00
Poster session
Session 2: Oligodendrocytes
14:00 – 15:00
Plenary Talk 2: The role glia cells in de- and remyelination
Mikael Simons, Technical University Munich and German Center for Neurodegenerative Diseases (DZNE)
15:00 – 15:30
The function of oligodendrocytes in AD
Klaus Armin Nave, U. Göttingen
15:30 – 15:45
Blitz Talks (selected from abstracts)
15:45 – 16:15
Coffee break (posters & industry exhibition)
Session 3: Astrocytes
16:15 – 16:45
Reactive astrocytes in neurodegeneration
Shane Liddelow, New York University
16:45 – 17:15
The epigenetic and metabolic control of astrocytes
Francisco Quintana, Harvard Medical School
Session 4: Epigenetics
17:15 – 18:15
Non-Coding RNAs and Epigenetic Regulation in Astrocytes and Microglia: Insights into Neurodegenerative Diseases
André Fischer, University Medical Center Göttingen and German Center for Neurodegenerative Diseases (DZNE)
18:15 – 18:45
Single-Cell and Spatial Transcriptomics and Epigenomics of Oligodendroglia in Development and in Multiple Sclerosis
Gonçalo Castelo-Branco, Karolinska Institute
Session 5: Inflammasomes & cGAS/STING
9:00 – 10:00
Plenary Talk 3: Inflammasomes: from fundamental biology to new therapeutics for neuroinflammation
Kate Schroeder, Institute for Molecular Bioscience, The University of Queensland
10:00 – 10:30
The role of cGAS/STING-IFN in tauopathies
Li Gan, Cornell University
10:30 – 11:00
Coffee break (posters & industry exhibition)
11:00 – 11:15
Blitz talks (selected from abstracts)
11:15 – 11:45
New insights on the regulation of the NLRP3 inflammasome
Bénédicte Py, International Center for Infectiology Research, Inserm
Session 6: Neurodegeneration
11:45 – 12:45
Plenary Talk 4: The interplay between tau pathology and neuroinflammation
Maria Grazia Spillantini, Cambridge University
12:45 – 13:45
Lunch (posters & industry exhibition)
13:45 – 14:15
Poster session & industry exhibition
14:15 – 14:45
The inflammatory regulation of APP processing and Aβ pathology
Magdalena Sastre, Imperial College London
14:45 – 15:15
Role of microglia/macrophage CD300f immune receptor in Alzheimer’s disease
Hugo Peluffo, University of Barcelona
15:15 – 15:30
Blitz talks (selected from abstracts)
15:30 – 16:00
Effects of glial senescence on neurodegeneration
Darren Baker, Mayo Clinic
16:00 – 16:30
Coffee break (posters & industry exhibition)
Session 7: Technical Developments
16:30 – 17:30
Plenary Talk 5: Divergent Neuro-Immune Interactions Shaping Disease and Aging: Insights from snRNA-seq
Naomi Habib, ELSC Center for Brain Sciences, Hebrew University of Jerusalem
17:30 – 17:45
Blitz talks (selected from abstracts)
17:45 – 18:15
The metabolome of the aging brain
Oliver Fiehn, University of California, Davis
18:15 – 18:45
TBC
18:45 – 21:30
Networking dinner with poster session and industry exhibition
Session 8: Clinical Aspects of Neuroinflammation
9:00 – 10:00
Plenary talk 6: Imaging of neuroinflammation
Paul Edison, Imperial College London
10:00 – 10:30
TBC
10:30 – 11:00
Coffee break (posters & industry exhibition)
11:30 – 12:00
Cellular communities drive trajectories leading to Alzheimer’s disease or alternative brain aging
Philip de Jager, Columbia University Medical Center
12:00 – 12:15
Blitz talks (selected from abstracts)
12:15 – 13:00
Lunch (posters & industry exhibition)
13:00 – 13:30
Poster session & industry exhibition
Section 9: Neurodegeneration Pathology
13:30 – 14:30
Plenary Talk 7: The structures of pathological amyloid filaments
Michel Goedert, Cambridge University
14:30 – 15:00
The impact of TDP-43 proteinopathy on neurodegeneration in Alzheimer’s disease and amyotrophic lateral sclerosis
Dietmar Thal, University of Leuven
15:00 – 15:15
Blitz talks (selected from abstracts)
15:15 – 15.45
Coffee break (posters & industry exhibition)
15:45 – 16:15
Role of microglial inflammation in progression of proteinopathies
Seung-Jae Lee, Seoul National University College of Medicine
Session 10: Neurotransmitters
16:15 – 17:15
Plenary Talk 8: Cholinergic-targeted transfer RNA fragments in health and brain diseases
Hermona Soreq, Edmond and Lily Safra Center for brain Sciences, Hebrew University
17:15 – 17:45
The role of type I interferon response in Alzheimer’s disease
Wei Cao, University of Texas Health Science Center Houston