8:45 – 9:00
Welcome words
Michael Heneka, Director, Luxembourg Centre for Systems Biomedicine
9:00 – 10:00
Keynote: Complement system in neurodegenerative disease
Cynthia Lemere, Harvard University
Session 1: Immunometabolism and lysosome function in neurodegenerative disease
10:00 – 10:30
Dietary modulation of microglial biology
Agnes Nadjar, University of Bordeaux
10:30 – 11:00
Coffee break, industry exhibition and posters
11:00 – 11:30
Lysosomal proteases in neurodegenerative disease
Aimee Kao, University of California San Francisco
11:00 – 11:30
Metabolic control of microglia
Rosa Chiara Paolicelli, University of Lausanne
12:00 – 12:15
2 Blitz Talks (selected from abstracts)
12:15 – 13:45
Lunch with industry exhibition and posters
13:45 – 14:00
Presentation of the Luxembourg National Research Fund
TBC
14:00 – 15:00
Keynote: Plasma proteomics linking the brain and immune system
Tony Wyss-Coray, Stanford University
Session 2: Resolvins role for shaping immune responses
15:00 – 15:30
Resolvins as therapeutic intervention in neurodegenerative disease
Marianne Schultzberg, Karolinska Institutet
15:30 – 16:00
Resolvin regulation of immune processes
Jesmond Dalli, Queen Mary University of London
16:00 – 16:30
Coffee break, industry exhibition and posters
Session 3: Microglia
16:30 – 17:00
Immune networks in the pathogenesis of Alzheimer’s disease
Bin Zhang, Icahn School of Medicine
17:00 – 17:30
Utilizing iPSC-derived microglia to study GWAS associated AD risk variants
Tracy L. Young-Pearse, Harvard University
17:30 – 18:00
Trem2 mysteries from loss and gain of function mutations in Alzheimer’s disease
Ana Griciuc, Harvard Medical School
18:00 – 18:15
2 Blitz Talks (selected from abstracts)
19:30 – onwards
Speakers’ dinner
9:00 – 10:00
Keynote: Prenatal immune impact
Sonia Garel, Institut de biologie de l’Ecole normale supérieure de Paris
Session 4: Astrocytes
10:00 – 10:30
TBC
10:30 – 10:45
2 Blitz Talks (selected from abstracts)
10:45 – 11:15
Coffee break, industry exhibition and posters
11:15 – 11:45
TBC
Session 5: Inflammation & epilepsy: what is the link?
11:45 – 12:15
Brain invasion by monocytes during epilepsy
Nicholas Varvel, Emory University
12:15 – 12:45
Role of inflammasome activation in epilepsy
John R Lukens, University of Virginia
12:45 – 13:00
2 Blitz Talks (selected from abstracts)
13:00 – 14:30
Lunch, industry exhibition and posters
Session 6: Inflammatory biomarkers in neurodegenerative disease
14:30 – 15:00
Is there an added value of inflammatory biomarkers in neurodegenerative disease diagnosis?
Henrik Zetterberg, University College London TBC
15:00 – 15:30
Inflammatory biomarkers in Fronto-temporal dementia
Anja Schneider, University Clinic Bonn
15:30 – 16:00
ASC speck detection in biofluids
David Klenerman, University of Cambridge
16:00 – 16:15
2 Blitz Talks (selected from abstracts)
16:15 – 16:45
Coffee break, industry exhibition and posters
Session 7: PET imaging on neuroinflammation
16:45 – 17:15
Imaging astrocytes in neurodegenerative disease
Agneta Nordberg, Karolinska Institutet
17:15 – 17:45
Glial inflammation and disease progression in neurodegeneration
Pedro Rosa-Neto, McGill University
17:45 – 18:45
Keynote
TBC
18:45 – 21:30
Networking dinner
Session 8: Brain to periphery and back
9:00 – 9:30
How stroke-related inflammation affects cardiac function
Arthur Liesz, LMU Munich
9:30 – 10:00
DNA methylation signatures of systemic inflammation
Keenan Walker, National Institutes of Health USA
10:00 – 10:30
Inflamed macrophages in Parkinson’s disease
David Hafler, Yale School of Medicine
10:30 – 11:00
Coffee break, industry exhibition and posters
Session 9: Interactions of the adaptive and innate immune systems
11:00 – 11:30
Applying spatial transcriptomics to track innate and adaptive immune responses
Lynn van Olst, Northwestern University
11:30 – 12:00
Role of endothelium for neuroinflammation in Parkinson’s disease
Jeffrey H. Kordower, Arizona State University TBC
12:00 – 12:15
2 Blitz Talks (selected from abstracts)
12:15 – 14:00
Lunch, industry exhibition and posters
Session 10: The viral hypothesis revisited
14:00 – 14:30
The viral hypothesis in Alzheimer’s disease
Ruth Itzhaki, The University of Manchester
14:30 – 15:00
Herpes virus action on glia and neurons
Georges Verjans, Erasmus MC
15:00 – 15:30
TLR9 impact on Alzheimer disease pathogenesis
Bénédicte Manoury, CNRS
16:00 – 16:30
Coffee break, industry exhibition and posters
Session 11: Cellular replacement strategies
16:00 – 16:30
Engineering microglia by AVV in vivo – recent developments
Hirokazu Hirai, Gunma University Graduate School of Medicine
16:30 – 17:00
CNS wide microglia replacement strategies
Mathew Blurton- Jones, University of California Irvine
17:00 – 17:30
Lessons from microglia replacement strategies in neurodegenerative disease models
Frederik Christian Bennett, University of Pennsylvania
17:30 – 17:45
Poster prize ceremony
17:45
Wrap up and closing