Paul Edison

Paul Edison is the Professor of Neuroscience and Clinical Professor in the Division of Neurology, Faculty of Medicine at Imperial College London. He leads several national and international multicentre studies and other initiatives evaluating Alzheimer’s disease, frontotemporal dementia and other neurodegenerative diseases in the US, Canada, Europe and Australia. He was the Editor-in-Chief of the journal BRAIN CONNECTIVITY.

Prof. Edison’s research has focused on neuroimaging with novel molecular probes using PET (Positron Emission Tomography) and magnetic resonance imaging (MRI) techniques for imaging pathophysiological changes associated with Alzheimer’s disease, Parkinson’s disease, and other neurodegenerative diseases. He has published seminal papers in the field of Alzheimer’s disease and other neurodegenerative diseases.  Combined with his clinical expertise in different types of degenerative diseases and dementia, he has investigated the complex relationship between amyloid deposition, microglial activation, and glucose metabolism in various disorders, along with evaluating different transporters in the brain. His pioneering work on the longitudinal trajectory of microglial activation demonstrated that early microglial activation could be protective while, during the later stages of the disease, microglial activation can have a deleterious effect highlighting the importance of targeting neuroinflammation differently in different stages of the disease.

His work has been published in different high-impact journals like BMJ (British Medical Journal), Nature journals, Nature Medicine, Nature Reviews Neurology, Lancet Neurology, Brain, Neurology, Annals of Neurology, Molecular Psychiatry, etc

Dr Edison is the Chief Investigator of several imaging and intervention studies using PET and MRI, and heads multicentre studies evaluating novel treatments for Alzheimer’s and other neurodegenerative diseases. He also runs a memory clinic at Imperial College Healthcare NHS Trust.