Lennart Mucke

As founding director of the Gladstone Institute of Neurological Disease and Joseph B. Martin Distinguished Professor of Neuroscience and Professor of Neurology at the University of California, San Francisco, Dr. Mucke has developed a premier program for research and training in disease-focused neuroscience. He has unraveled pathophysiological mechanisms of cognitive decline in Alzheimer’s disease (AD) and identified unexpected links among AD, epilepsy and autism spectrum disorders, as well as related entry points for novel interventions that could be of therapeutic benefit in multiple neurologic and psychiatric conditions. Dr. Mucke has a long-standing interest in neuroimmunology and has used a variety of genetically modified mouse models to differentiate adaptive from maladaptive interactions between neurons and glial cells. Dr. Mucke is an elected member of the U.S. National Academy of Medicine and has received the Potamkin Prize, MetLife Foundation Award for Medical Research, and Khalid Iqbal Lifetime Achievement Award. He has served on the National Advisory Council on Aging for the U.S. National Institutes of Health and chaired the Senate of the German Center for Neurodegenerative Diseases. Dr. Mucke trained at the Free University Berlin, Georg-August University and Max Planck Institute for Biophysical Chemistry in Göttingen, Cleveland Clinic, Massachusetts General Hospital, Harvard Medical School, and The Scripps Research Institute.